Compile Data Set for Download or QSAR
Found 5 of Enz. Inhib. data with enzyme = 'Beta-secretase 2' and Substrate = 'BACE Peptide Substrate'
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM16755(Acylguanidine, 10d | N-[(1Z)-amino[(3-hydroxypropy...)copy SMILEScopy InChI
Affinity DataIC50: 340nMpH: 4.5 T: 2°CAssay Description:A homogenous, continuous fluorescence resonance energy transfer (FRET) assay was used to assess compound inhibition of enzyme based on the cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043NGPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM16753(2-[2-(2-chlorophenyl)-5-[4-(4-acetylphenoxy)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMpH: 4.5 T: 2°CAssay Description:A homogenous, continuous fluorescence resonance energy transfer (FRET) assay was used to assess compound inhibition of enzyme based on the cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043NGPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM16754(2-[2-(adamantan-1-yl)-5-phenyl-1H-pyrrol-1-yl]-N-[...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMpH: 4.5 T: 2°CAssay Description:A homogenous, continuous fluorescence resonance energy transfer (FRET) assay was used to assess compound inhibition of enzyme based on the cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043NGPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM16752(2-[2-(adamantan-1-yl)-5-phenyl-1H-pyrrol-1-yl]-N-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.29E+4nMpH: 4.5 T: 2°CAssay Description:A homogenous, continuous fluorescence resonance energy transfer (FRET) assay was used to assess compound inhibition of enzyme based on the cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043NGPubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM16751((N-(diaminomethylene)-2,4-diphenyl-1H-pyrrole-1-ac...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMpH: 4.5 T: 2°CAssay Description:A homogenous, continuous fluorescence resonance energy transfer (FRET) assay was used to assess compound inhibition of enzyme based on the cleavage o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043NGPubMed